1. Froiland K, Koszewski W, Hingst J, Kopecky L: Nutritional supplement use
among college athletes and their sources of information. Int J Sport Nutr
Exerc Metab 2004, 14:104–120.
2. Hoffman: Caffeine and Energy Drinks. Strength Cond J 2010, 32:15–20.
3. Hoffman JR, Faigenbaum AD, Ratamess NA, Ross R, Kang J, Tenenbaum G:
Nutritional supplementation and anabolic steroid use in adolescents.
Med Sci Sports Exerc 2008, 40:15–24.
4. Petroczi A, Naughton DP, Pearce G, Bailey R, Bloodworth A, McNamee M:
Nutritional supplement use by elite young UK athletes: fallacies of
advice regarding efficacy. J Int Soc Sports Nutr 2008, 5:22.
5. Wolk BJ, Ganetsky M, Babu KM: Toxicity of energy drinks. Curr Opin Pediatr
6. Kerksick C, Harvey T, Stout J, Campbell B, Wilborn C, Kreider R, Kalman D,
Ziegenfuss T, Lopez H, Landis J, et al: International Society of Sports
Nutrition position stand: nutrient timing. J Int Soc Sports Nutr 2008, 5:17.
7. Goldstein ER, Ziegenfuss T, Kalman D, Kreider R, Campbell B, Wilborn C,
Taylor L, Willoughby D, Stout J, Graves BS, et al: International society of
sports nutrition position stand: caffeine and performance. J Int Soc Sports
Nutr 2010, 7:5.
8. Bonati M, Latini R, Galletti F, Young JF, Tognoni G, Garattini S:
Caffeine disposition after oral doses. Clin Pharmacol Ther 1982, 32:98–106.
9. Graham TE, Hibbert E, Sathasivam P: Metabolic and exercise endurance
effects of coffee and caffeine ingestion. J Appl Physiol 1998, 85:883–889.
10. McLellan TM, Bell DG: The impact of prior coffee consumption on the
subsequent ergogenic effect of anhydrous caffeine. Int J Sport Nutr Exerc
Metab 2004, 14:698–708.
11. Kovacs EM, Stegen J, Brouns F: Effect of caffeinated drinks on substrate
metabolism, caffeine excretion, and performance. J Appl Physiol 1998,
12. Oka H, Suzuki S, Suzuki H, Oda T: Increased urinary excretion of L-xylulose
in patients with liver cirrhosis. Clin Chim Acta 1976, 67:131–136.
13. Jeukendrup A, Brouns F, Wagenmakers AJ, Saris WH: Carbohydrate-electrolyte
feedings improve 1 h time trial cycling performance. Int J Sports Med 1997,
14. Jeukendrup AE: Carbohydrate intake during exercise and performance.
Nutrition 2004, 20:669–677.
15. Coyle EF, Coggan AR, Hemmert MK, Ivy JL: Muscle glycogen utilization
during prolonged strenuous exercise when fed carbohydrate. J Appl
Physiol 1986, 61:165–172.
16. Jeukendrup AE, Jentjens R: Oxidation of carbohydrate feedings during
prolonged exercise: current thoughts, guidelines and directions for
future research. Sports Med 2000, 29:407–424.
17. Kreider RB, Wilborn CD, Taylor L, Campbell B, Almada AL, Collins R, Cooke M,
Earnest CP, Greenwood M, Kalman DS, et al: ISSN exercise & sport nutrition
review: research & recommendations. J Int Soc Sports Nutr 2010, 7:7.
18. Rodriguez NR, Di Marco NM, Langley S: American College of Sports
Medicine position stand. Nutrition and athletic performance. Med Sci
Sports Exerc 2009, 41:709–731.
19. Murray R, Bartoli W, Stofan J, Horn M, Eddy D: A comparison of the gastric
emptying characteristics of selected sports drinks. Int J Sport Nutr 1999,
20. Maughan RJ, Leiper JB: Limitations to fluid replacement during exercise.
Can J Appl Physiol 1999, 24:173–187.
21. Franconi F, Loizzo A, Ghirlanda G, Seghieri G: Taurine supplementation
and diabetes mellitus. Curr Opin Clin Nutr Metab Care 2006, 9:32–36.
22. Dawson R Jr, Biasetti M, Messina S, Dominy J: The cytoprotective role of
taurine in exercise-induced muscle injury. Amino Acids 2002, 22:309–324.
23. Zhang M, Izumi I, Kagamimori S, Sokejima S, Yamagami T, Liu Z, Qi B:
Role of taurine supplementation to prevent exercise-induced oxidative
stress in healthy young men. Amino Acids 2004, 26:203–207.
24. Obrosova IG, Stevens MJ: Effect of dietary taurine supplementation on GSH and
NAD(P)-redox status, lipid peroxidation, and energy metabolism in diabetic
precataractous lens. Invest Ophthalmol Vis Sci 1999, 40:680–688.
25. Bakker AJ, Berg HM: Effect of taurine on sarcoplasmic reticulum function
and force in skinned fast-twitch skeletal muscle fibres of the rat. J Physiol
26. Bichler A, Swenson A, Harris MA: A combination of caffeine and taurine
has no effect on short term memory but induces changes in heart rate
and mean arterial blood pressure. Amino Acids 2006, 31:471–476.
27. Galloway SD, Talanian JL, Shoveller AK, Heigenhauser GJ, Spriet LL:
Seven days of oral taurine supplementation does not increase muscle
taurine content or alter substrate metabolism during prolonged exercise
in humans. J Appl Physiol 2008, 105:643–651.
28. Matsuzaki Y, Miyazaki T, Miyakawa S, Bouscarel B, Ikegami T, Tanaka N:
Decreased taurine concentration in skeletal muscles after exercise for
various durations. Med Sci Sports Exerc 2002, 34:793–797.
29. Rutherford JA, Spriet LL, Stellingwerff T: The effect of acute taurine
ingestion on endurance performance and metabolism in well-trained
cyclists. Int J Sport Nutr Exerc Metab 2010, 20:322–329.
30. Ward RJ, Francaux M, Cuisinier C, Sturbois X, De Witte P: Changes in
plasma taurine levels after different endurance events. Amino Acids 1999,
31. Seidl R, Peyrl A, Nicham R, Hauser E: A taurine and caffeine-containing
drink stimulates cognitive performance and well-being. Amino Acids
32. Goodman CA, Horvath D, Stathis C,Mori T, Croft K, Murphy RM, Hayes A: Taurine
supplementation increases skeletal muscle force production and protects
muscle function during and after high-frequency in vitro stimulation. J Appl
Physiol 2009, 107:144–154.
33. Wang FR, Dong XF, Tong JM, Zhang XM, Zhang Q, Wu YY: Effects of
dietary taurine supplementation on growth performance and immune
status in growing Japanese quail (Coturnix coturnix japonica). Poult Sci
34. Pierno S, De Luca A, Camerino C, Huxtable RJ, Camerino DC: Chronic
administration of taurine to aged rats improves the electrical and contractile
properties of skeletal muscle fibers. J Pharmacol Exp Ther 1998, 286:1183–1190.
35. Warburton DM, Bersellini E, Sweeney E: An evaluation of a caffeinated
taurine drink on mood, memory and information processing in healthy
volunteers without caffeine abstinence. Psychopharmacology (Berl) 2001,
36. Jorm AF, Rodgers B, Christensen H: Use of medications to enhance memory in a
large community sample of 60-64 year olds. Int Psychogeriatr 2004, 16:209–217.
37. Elsabagh S, Hartley DE, File SE: Limited cognitive benefits in Stage +2
postmenopausal women after 6 weeks of treatment with Ginkgo biloba.
J Psychopharmacol 2005, 19:173–181.
38. Walesiuk A, Trofimiuk E, Braszko JJ: Gingko biloba extract diminishes
stress-induced memory deficits in rats. Pharmacol Rep 2005, 57:176–187.
39. Stoll S, Scheuer K, Pohl O, Muller WE: Ginkgo biloba extract (EGb 761)
independently improves changes in passive avoidance learning and
brain membrane fluidity in the aging mouse. Pharmacopsychiatry 1996,
40. Grevet EH, Tietzmann MR, Shansis FM, Hastenpflugl C, Santana LC, Forster L,
Kapczinskil F, Izquierdo I: Behavioural effects of acute phenylalanine and
tyrosine depletion in healthy male volunteers. J Psychopharmacol 2002,
41. Mahoney CR, Castellani J, Kramer FM, Young A, Lieberman HR: Tyrosine
supplementation mitigates working memory decrements during cold
exposure. Physiol Behav 2007, 92:575–582.
42. Chinevere TD, Sawyer RD, Creer AR, Conlee RK, Parcell AC:
Effects of L-tyrosine and carbohydrate ingestion on endurance exercise
performance. J Appl Physiol 2002, 93:1590–1597.
43. Deijen JB, Wientjes CJ, Vullinghs HF, Cloin PA, Langefeld JJ:
Tyrosine improves cognitive performance and reduces blood pressure in
cadets after one week of a combat training course. Brain Res Bull 1999,
44. Salter CA: Dietary tyrosine as an aid to stress resistance among troops.
Mil Med 1989, 154:144–146.
45. Smith ML, Hanley WB, Clarke JT, Klim P, Schoonheyt W, Austin V,
Lehotay DC: Randomised controlled trial of tyrosine supplementation on
neuropsychological performance in phenylketonuria. Arch Dis Child 1998,
46. Magill RA, Waters WF, Bray GA, Volaufova J, Smith SR, Lieberman HR,
McNevin N, Ryan DH: Effects of tyrosine, phentermine,
caffeine D-amphetamine, and placebo on cognitive and motor
performance deficits during sleep deprivation. Nutr Neurosci 2003,
47. Waters WF, Magill RA, Bray GA, Volaufova J, Smith SR, Lieberman HR, Rood J,
Hurry M, Anderson T, Ryan DH: A comparison of tyrosine against placebo,
phentermine, caffeine, and D-amphetamine during sleep deprivation.
Nutr Neurosci 2003, 6:221–235.
48. O'Brien C, Mahoney C, Tharion WJ, Sils IV, Castellani JW: Dietary tyrosine
benefits cognitive and psychomotor performance during body cooling.
Physiol Behav 2007, 90:301–307.
49. Wiesel FA, Edman G, Flyckt L, Eriksson A, Nyman H, Venizelos N,
Bjerkenstedt L: Kinetics of tyrosine transport and cognitive functioning in
schizophrenia. Schizophr Res 2005, 74:81–89.
50. Struder HK, Hollmann W, Platen P, Donike M, Gotzmann A, Weber K:
Influence of paroxetine, branched-chain amino acids and tyrosine on
neuroendocrine system responses and fatigue in humans. Horm Metab
Res 1998, 30:188–194.
51. Jager R, Purpura M, Kingsley M: Phospholipids and sports performance.
J Int Soc Sports Nutr 2007, 4:5.
52. Warber JP, Patton JF, Tharion WJ, Zeisel SH, Mello RP, Kemnitz CP,
Lieberman HR: The effects of choline supplementation on physical
performance. Int J Sport Nutr Exerc Metab 2000, 10:170–181.
53. Turner EH, Loftis JM, Blackwell AD: Serotonin a la carte: supplementation
with the serotonin precursor 5-hydroxytryptophan. Pharmacol Ther 2006,
54. Chaouloff F, Laude D, Elghozi JL: Physical exercise: evidence for differential
consequences of tryptophan on 5-HT synthesis and metabolism in central
serotonergic cell bodies and terminals. J Neural Transm 1989, 78:121–130.
55. Leu-Semenescu S, Arnulf I, Decaix C, Moussa F, Clot F, Boniol C, Touitou Y,
Levy R, Vidailhet M, Roze E: Sleep and rhythm consequences of a
genetically induced loss of serotonin. Sleep 2010, 33:307–314.
56. Freeman MP, Helgason C, Hill RA: Selected integrative medicine
treatments for depression: considerations for women. J Am Med Womens
Assoc 2004, 59:216–224.
57. Larzelere MM, Wiseman P: Anxiety, depression, and insomnia.
Prim Care 2002, 29:339–360. vii.
58. Thachil AF, Mohan R, Bhugra D: The evidence base of complementary and
alternative therapies in depression. J Affect Disord 2007, 97:23–35.
59. Hayashi Y, Jacob-Vadakot S, Dugan EA, McBride S, Olexa R, Simansky K,
Murray M, Shumsky JS: 5-HT precursor loading, but not 5-HT receptor
agonists, increases motor function after spinal cord contusion in adult
rats. Exp Neurol 2010, 221:68–78.
60. Yamamoto T, Newsholme EA: Diminished central fatigue by inhibition of
the L-system transporter for the uptake of tryptophan. Brain Res Bull
61. Heckman MA, Weil J, Gonzalez de Mejia E: Caffeine (1, 3, 7-trimethylxanthine) in
foods: a comprehensive review on consumption, functionality, safety, and
regulatory matters. J Food Sci 2010, 75:R77–87.
62. Ivy JL, Kammer L, Ding Z, Wang B, Bernard JR, Liao YH, Hwang J: Improved
cycling time-trial performance after ingestion of a caffeine energy drink.
Int J Sport Nutr Exerc Metab 2009, 19:61–78.
63. Goldstein E, Jacobs PL, Whitehurst M, Penhollow T, Antonio J:
Caffeine enhances upper body strength in resistance-trained women.
J Int Soc Sports Nutr 2010, 7:18.
64. Del Coso J, Muñoz-Fernández VE, Muñoz G, Fernández-Elías VE, Ortega JF,
Hamouti N, Barbero JC, Muñoz-Guerra J: Effects of a Caffeine-Containing
Energy Drink on Simulated Soccer Performance. PLoS One 2012, 7:e31380.
65. Del Coso J, Salinero JJ, Gonzalez-Millan C, Abian-Vicen J, Perez-Gonzalez B:
Dose response effects of a caffeine-containing energy drink on muscle
performance: a repeated measures design. J Int Soc Sports Nutr 2012, 9:21.
66. Berube-Parent S, Pelletier C, Dore J, Tremblay A: Effects of encapsulated
green tea and Guarana extracts containing a mixture of
epigallocatechin-3-gallate and caffeine on 24 h energy expenditure and
fat oxidation in men. Br J Nutr 2005, 94:432–436.
67. Belza A, Toubro S, Astrup A: The effect of caffeine, green tea and tyrosine
on thermogenesis and energy intake. Eur J Clin Nutr 2009, 63:57–64.
68. Eichenberger P, Colombani PC, Mettler S: Effects of 3-week consumption
of green tea extracts on whole-body metabolism during cycling exercise
in endurance-trained men. Int J Vitam Nutr Res 2009, 79:24–33.
69. Venables MC, Hulston CJ, Cox HR, Jeukendrup AE: Green tea extract
ingestion, fat oxidation, and glucose tolerance in healthy humans.
Am J Clin Nutr 2008, 87:778–784.
70. Eichenberger P, Mettler S, Arnold M, Colombani PC: No Effects of Threeweek
Consumption of a Green Tea Extract on Time Trial Performance in
Endurance-trained Men. Int J Vitam Nutr Res 2010, 80:54–64.
71. Chen N, Bezzina R, Hinch E, Lewandowski PA, Cameron-Smith D, Mathai ML,
Jois M, Sinclair AJ, Begg DP, Wark JD, et al: Green tea, black tea, and
epigallocatechin modify body composition, improve glucose tolerance,
and differentially alter metabolic gene expression in rats fed a high-fat
diet. Nutr Res 2009, 29:784–793.
72. Hursel R, Westerterp-Plantenga MS: Green tea catechin plus caffeine
supplementation to a high-protein diet has no additional effect on body
weight maintenance after weight loss. Am J Clin Nutr 2009, 89:822–830.
73. Auvichayapat P, Prapochanung M, Tunkamnerdthai O, Sripanidkulchai BO,
Auvichayapat N, Thinkhamrop B, Kunhasura S, Wongpratoom S, Sinawat S,
Hongprapas P: Effectiveness of green tea on weight reduction in obese
Thais: A randomized, controlled trial. Physiol Behav 2008, 93:486–491.
74. Diepvens K, Kovacs EM, Nijs IM, Vogels N, Westerterp-Plantenga MS:
Effect of green tea on resting energy expenditure and substrate oxidation
during weight loss in overweight females. Br J Nutr 2005, 94:1026–1034.
75. Diepvens K, Westerterp KR, Westerterp-Plantenga MS: Obesity and
thermogenesis related to the consumption of caffeine, ephedrine,
capsaicin, and green tea. Am J Physiol Regul Integr Comp Physiol 2007,
76. Murase T, Haramizu S, Shimotoyodome A, Tokimitsu I, Hase T:
Green tea extract improves running endurance in mice by stimulating
lipid utilization during exercise. Am J Physiol Regul Integr Comp Physiol
77. Fugh-Berman A, Myers A: Citrus aurantium, an ingredient of dietary
supplements marketed for weight loss: current status of clinical and
basic research. Exp Biol Med (Maywood) 2004, 229:698–704.
78. Haller CA, Benowitz NL, Jacob P 3rd: Hemodynamic effects of ephedra-free
weight-loss supplements in humans. Am J Med 2005, 118:998–1003.
79. KimGS, Park HJ, Woo JH, KimMK, Koh PO, MinW, Ko YG, KimCH,Won CK, Cho
JH: Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling
pathway in 3T3-L1 cells. BMC Complement Altern Med 2012, 12:31.
80. Peixoto JS, Comar JF, Moreira CT, Soares AA, de Oliveira AL, Bracht A, Peralta RM:
Effects of Citrus aurantium (bitter orange) fruit extracts and p-synephrine on
metabolic fluxes in the rat liver. Molecules 2012, 17:5854–5869.
81. Preuss HG, DiFerdinando D, Bagchi M, Bagchi D: Citrus aurantium as a
thermogenic, weight-reduction replacement for ephedra: an overview.
J Med 2002, 33:247–264.
82. Stohs SJ, Preuss HG, Keith SC, Keith PL, Miller H, Kaats GR: Effects of
p-synephrine alone and in combination with selected bioflavonoids on
resting metabolism, blood pressure, heart rate and self-reported mood
changes. Int J Med Sci 2011, 8:295–301.
83. Pittler MH, Ernst E: Dietary supplements for body-weight reduction:
a systematic review. Am J Clin Nutr 2004, 79:529–536.
84. Pittler MH, Schmidt K, Ernst E: Adverse events of herbal food supplements
for body weight reduction: systematic review. Obes Rev 2005, 6:93–111.
85. Kang YR, Lee HY, Kim JH, Moon DI, Seo MY, Park SH, Choi KH,
Kim CR, Kim SH, Oh JH, et al: Anti-obesity and anti-diabetic effects of
Yerba Mate (Ilex paraguariensis) in C57BL/6J mice fed a high-fat diet.
Lab Anim Res 2012, 28:23–29.
86. Riley AJ: Yohimbine in the treatment of erectile disorder. Br J Clin Pract
87. Gupta RS, Sharma R, Sharma A, Bhatnager AK, Dobhal MP, Joshi YC, Sharma MC:
Effect of Alstonia scholaris bark extract on testicular function of Wistar rats.
Asian J Androl 2002, 4:175–178.
88. Porst H: The future of erectile dysfunction (ED). Arch Esp Urol 2010, 63:740–747.
89. Kucio C, Jonderko K, Piskorska D: Does yohimbine act as a slimming drug?
Isr J Med Sci 1991, 27:550–556.
90. Sax L: Yohimbine does not affect fat distribution in men. Int J Obes 1991,
91. deMarcaida JA, Schwid SR, White WB, Blindauer K, Fahn S, Kieburtz K, Stern
M, Shoulson I: Effects of tyramine administration in Parkinson's disease
patients treated with selective MAO-B inhibitor rasagiline. Mov Disord
92. Conlay LA, Maher TJ, Wurtman RJ: Tyrosine's pressor effect in hypotensive
rats is not mediated by tyramine. Life Sci 1984, 35:1207–1212.
93. Edwards DJ: Possible role of octopamine and tyramine in the antihypertensive
and antidepressant effects of tyrosine. Life Sci 1982, 30:1427–1434.
94. McDaniel MA, Maier SF, Einstein GO: "Brain-specific" nutrients: a memory
cure? Nutrition 2003, 19:957–975.
95. Polich J, Gloria R: Cognitive effects of a Ginkgo biloba/vinpocetine
compound in normal adults: systematic assessment of perception,
attention and memory. Hum Psychopharmacol 2001, 16:409–416.
96. Bahrke MS, Morgan WP, Stegner A: Is ginseng an ergogenic aid? Int J Sport
Nutr Exerc Metab 2009, 19:298–322.
97. Engels HJ, Fahlman MM, Wirth JC: Effects of ginseng on secretory IgA,
performance, and recovery from interval exercise. Med Sci Sports Exerc
98. Goulet ED, Dionne IJ: Assessment of the effects of eleutherococcus senticosus
on endurance performance. Int J Sport Nutr Exerc Metab 2005, 15:75–83.
99. Hsu CC, Ho MC, Lin LC, Su B, Hsu MC: American ginseng supplementation
attenuates creatine kinase level induced by submaximal exercise in
human beings. World J Gastroenterol 2005, 11:5327–5331.
100. Hwang HJ, Kwak YS, Yoon GA, Kang MH, Park JH, Lee BK, Kim SJ, Um SY,
Kim YM: Combined effects of swim training and ginseng
supplementation on exercise performance time, ROS, lymphocyte
proliferation, and DNA damage following exhaustive exercise stress.
Int J Vitam Nutr Res 2007, 77:289–296.
101. Kulaputana O, Thanakomsirichot S, Anomasiri W: Ginseng supplementation
does not change lactate threshold and physical performances in
physically active Thai men. J Med Assoc Thai 2007, 90:1172–1179.
102. Liang MT, Podolka TD, Chuang WJ: Panax notoginseng supplementation
enhances physical performance during endurance exercise.
J Strength Cond Res 2005, 19:108–114.
103. Reay JL, Scholey AB, Milne A, Fenwick J, Kennedy DO: Panax ginseng has
no effect on indices of glucose regulation following acute or chronic
ingestion in healthy volunteers. Br J Nutr 2009, 101:1673–1678.
104. Engels HJ, Kolokouri I, Cieslak TJ 2nd, Wirth JC: Effects of ginseng supplementation
on supramaximal exercise performance and short-term recovery. J Strength
Cond Res 2001, 15:290–295.
105. Eschbach LF, Webster MJ, Boyd JC, McArthur PD, Evetovich TK: The effect
of siberian ginseng (Eleutherococcus senticosus) on substrate utilization
and performance. Int J Sport Nutr Exerc Metab 2000, 10:444–451.
106. Ferrando A, Vila L, Voces JA, Cabral AC, Alvarez AI, Prieto JG: Effects of
ginseng extract on various haematological parameters during aerobic
exercise in the rat. Planta Med 1999, 65:288–290.
107. Ferrando A, Vila L, Voces JA, Cabral AC, Alvarez AI, Prieto JG: Effects of a
standardized Panax ginseng extract on the skeletal muscle of the rat: a
comparative study in animals at rest and under exercise. Planta Med
108. Ziemba AW, Chmura J, Kaciuba-Uscilko H, Nazar K, Wisnik P, Gawronski W:
Ginseng treatment improves psychomotor performance at rest and
during graded exercise in young athletes. Int J Sport Nutr 1999,
109. Allen JD, McLung J, Nelson AG, Welsch M: Ginseng supplementation does
not enhance healthy young adults' peak aerobic exercise performance.
J Am Coll Nutr 1998, 17:462–466.
110. Engels HJ, Wirth JC: No ergogenic effects of ginseng (Panax ginseng C.A.
Meyer) during graded maximal aerobic exercise. J Am Diet Assoc 1997,
111. Pieralisi G, Ripari P, Vecchiet L: Effects of a standardized ginseng extract
combined with dimethylaminoethanol bitartrate, vitamins, minerals, and
trace elements on physical performance during exercise. Clin Ther 1991,
112. Karlic H, Lohninger A: Supplementation of L-carnitine in athletes: does it
make sense? Nutrition 2004, 20:709–715.
113. Pauly DF, Pepine CJ: D-Ribose as a supplement for cardiac energy metabolism.
J Cardiovasc Pharmacol Ther 2000, 5:249–258.
114. Kerksick C, Rasmussen C, Bowden R, Leutholtz B, Harvey T, Earnest C,
Greenwood M, Almada A, Kreider R: Effects of ribose supplementation
prior to and during intense exercise on anaerobic capacity and
metabolic markers. Int J Sport Nutr Exerc Metab 2005, 15:653–664.
115. Kreider RB, Melton C, Greenwood M, Rasmussen C, Lundberg J, Earnest C,
Almada A: Effects of oral D-ribose supplementation on anaerobic
capacity and selected metabolic markers in healthy males. Int J Sport
Nutr Exerc Metab 2003, 13:76–86.
116. Berardi JM, Ziegenfuss TN: Effects of ribose supplementation on repeated
sprint performance in men. J Strength Cond Res 2003, 17:47–52.
117. Dunne L, Worley S, Macknin M: Ribose versus dextrose supplementation,
association with rowing performance: a double-blind study. Clin J Sport
Med 2006, 16:68–71.
118. Eijnde BO, Van Leemputte M, Brouns F, Van Der Vusse GJ, Labarque V,
Ramaekers M, Van Schuylenberg R, Verbessem P, Wijnen H, Hespel P: No
effects of oral ribose supplementation on repeated maximal exercise
and de novo ATP resynthesis. J Appl Physiol 2001, 91:2275–2281.
119. Hellsten Y, Skadhauge L, Bangsbo J: Effect of ribose supplementation on
resynthesis of adenine nucleotides after intense intermittent training in
humans. Am J Physiol Regul Integr Comp Physiol 2004, 286:R182–188.
120. Harris RC, Sale C: Beta-alanine supplementation in high-intensity exercise.
Med Sport Sci 2013, 59:1–17.
121. Hoffman JR, Emerson NS, Stout JR: beta-Alanine supplementation. Curr Sports
Med Rep 2012, 11:189–195.
122. Harris RC, Wise JA, Price KA, Kim HJ, Kim CK, Sale C: Determinants of
muscle carnosine content. Amino Acids 2012, 43:5–12.
123. Culbertson JY, Kreider RB, Greenwood M, Cooke M: Effects of beta-alanine
on muscle carnosine and exercise performance: a review of the current
literature. Nutrients 2010, 2:75–98.
124. Hobson RM, Saunders B, Ball G, Harris RC, Sale C: Effects of beta-alanine
supplementation on exercise performance: a meta-analysis. Amino Acids
125. Smith-Ryan AE, Fukuda DH, Stout JR, Kendall KL: High-velocity intermittent
running: effects of beta-alanine supplementation. J Strength Cond Res
126. Saunders B, Sunderland C, Harris RC, Sale C: beta-alanine supplementation
improves YoYo intermittent recovery test performance. J Int Soc Sports
Nutr 2012, 9:39.
127. Jagim AR, Wright GA, Brice AG, Doberstein ST: Effects of beta-alanine
supplementation on sprint endurance. J Strength Cond Res 2012.
128. Sale C, Saunders B, Hudson S, Wise JA, Harris RC, Sunderland CD: Effect of
beta-alanine plus sodium bicarbonate on high-intensity cycling capacity.
Med Sci Sports Exerc 2011, 43:1972–1978.
129. Kern BD, Robinson TL: Effects of beta-alanine supplementation on
performance and body composition in collegiate wrestlers and football
players. J Strength Cond Res 2011, 25:1804–1815.
130. Walter AA, Smith AE, Kendall KL, Stout JR, Cramer JT: Six weeks of high-intensity
interval training with and without beta-alanine supplementation for improving
cardiovascular fitness in women. J Strength Cond Res 2010, 24:1199–1207.
131. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST: The effect of
beta-alanine supplementation on power performance during repeated
sprint activity. J Strength Cond Res 2010, 24:79–87.
132. Sale C, Saunders B, Harris RC: Effect of beta-alanine supplementation on
muscle carnosine concentrations and exercise performance. Amino Acids
133. Van Thienen R, Van Proeyen K, Vanden Eynde B, Puype J, Lefere T, Hespel P:
Beta-alanine improves sprint performance in endurance cycling. Med Sci
Sports Exerc 2009, 41:898–903.
134. Smith AE, Moon JR, Kendall KL, Graef JL, Lockwood CM, Walter AA, Beck TW,
Cramer JT, Stout JR: The effects of beta-alanine supplementation and
high-intensity interval training on neuromuscular fatigue and muscle
function. Eur J Appl Physiol 2009, 105:357–363.
135. Kendrick IP, Kim HJ, Harris RC, Kim CK, Dang VH, Lam TQ, Bui TT, Wise JA:
The effect of 4 weeks beta-alanine supplementation and isokinetic
training on carnosine concentrations in type I and II human skeletal
muscle fibres. Eur J Appl Physiol 2009, 106:131–138.
136. Stout JR, Graves BS, Smith AE, Hartman MJ, Cramer JT, Beck TW, Harris RC:
The effect of beta-alanine supplementation on neuromuscular fatigue in
elderly (55-92 Years): a double-blind randomized study. J Int Soc Sports
Nutr 2008, 5:21.
137. Hoffman JR, Ratamess NA, Faigenbaum AD, Ross R, Kang J, Stout JR,
Wise JA: Short-duration beta-alanine supplementation increases training
volume and reduces subjective feelings of fatigue in college football
players. Nutr Res 2008, 28:31–35.
138. Zoeller RF, Stout JR, O'Kroy JA, Torok DJ, Mielke M: Effects of 28 days of
beta-alanine and creatine monohydrate supplementation on aerobic
power, ventilatory and lactate thresholds, and time to exhaustion.
Amino Acids 2007, 33:505–510.
139. Einat H, Belmaker RH: The effects of inositol treatment in animal models
of psychiatric disorders. J Affect Disord 2001, 62:113–121.
140. Sureda A, Pons A: Arginine and citrulline supplementation in sports and
exercise: ergogenic nutrients? Med Sport Sci 2013, 59:18–28.
141. Bescos R, Sureda A, Tur JA, Pons A: The effect of nitric-oxide-related
supplements on human performance. Sports Med 2012, 42:99–117.
142. Bendahan D, Mattei JP, Ghattas B, Confort-Gouny S, Le Guern ME, Cozzone
PJ: Citrulline/malate promotes aerobic energy production in human
exercising muscle. Br J Sports Med 2002, 36:282–289.
143. Figueroa A, Trivino JA, Sanchez-Gonzalez MA, Vicil F: Oral L-citrulline
supplementation attenuates blood pressure response to cold pressor
test in young men. Am J Hypertens 2010, 23:12–16.
144. Hickner RC, Tanner CJ, Evans CA, Clark PD, Haddock A, Fortune C, Geddis H,
Waugh W, McCammon M: L-citrulline reduces time to exhaustion and insulin
response to a graded exercise test. Med Sci Sports Exerc 2006, 38:660–666.
145. Meneguello MO, Mendonca JR, Lancha AH Jr, Costa Rosa LF: Effect of
arginine, ornithine and citrulline supplementation upon performance
and metabolism of trained rats. Cell Biochem Funct 2003, 21:85–91.
146. Nagaya N, Uematsu M, Oya H, Sato N, Sakamaki F, Kyotani S, Ueno K, Nakanishi
N, Yamagishi M, Miyatake K: Short-term oral administration of L-arginine
improves hemodynamics and exercise capacity in patients with
precapillary pulmonary hypertension. Am J Respir Crit Care Med 2001,
147. Perez-Guisado J, Jakeman PM: Citrulline malate enhances athletic
anaerobic performance and relieves muscle soreness. J Strength Cond Res
148. Sureda A, Cordova A, Ferrer MD, Perez G, Tur JA, Pons A: L-citrulline-malate
influence over branched chain amino acid utilization during exercise.
Eur J Appl Physiol 2010, 110:341–351.
149. Takeda K, Machida M, Kohara A, Omi N, Takemasa T: Effects of citrulline
supplementation on fatigue and exercise performance in mice. J Nutr Sci
Vitaminol (Tokyo) 2011, 57:246–250.
150. Kressler J, Millard-Stafford M, Warren GL: Quercetin and endurance
exercise capacity: a systematic review and meta-analysis. Med Sci Sports
Exerc 2011, 43:2396–2404.
151. Wu J, Gao W, Wei J, Yang J, Pu L, Guo C: Quercetin alters energy
metabolism in swimming mice. Appl Physiol Nutr Metab 2012, 37:912–922.
152. Sharp MA, Hendrickson NR, Staab JS, McClung HL, Nindl BC, Michniak-Kohn
BB: Effects of short-term quercetin supplementation on soldier
performance. J Strength Cond Res 2012, 26(Suppl 2):S53–60.
153. O'Fallon KS, Kaushik D, Michniak-Kohn B, Dunne CP, Zambraski EJ, Clarkson
PM: Quercetin does not attenuate changes in markers of muscle
function or inflammation after eccentric exercise. Int J Sport Nutr Exerc
Metab 2012, .
154. Konrad M, Nieman DC, Henson DA, Kennerly KM, Jin F, Wallner-Liebmann
SJ: The acute effect of ingesting a quercetin-based supplement on
exercise-induced inflammation and immune changes in runners.
Int J Sport Nutr Exerc Metab 2011, 21:338–346.
155. Abbey EL, Rankin JW: Effect of quercetin supplementation on repeatedsprint
performance, xanthine oxidase activity, and inflammation. Int J
Sport Nutr Exerc Metab 2011, 21:91–96.
156. Nieman DC, Williams AS, Shanely RA, Jin F, McAnulty SR, Triplett NT, Austin
MD, Henson DA: Quercetin's influence on exercise performance and
muscle mitochondrial biogenesis. Med Sci Sports Exerc 2010, 42:338–345.
157. Ganio MS, Armstrong LE, Johnson EC, Klau JF, Ballard KD, Michniak-Kohn B,
Kaushik D, Maresh CM: Effect of quercetin supplementation on maximal
oxygen uptake in men and women. J Sports Sci 2010, 28:201–208.
158. Bigelman KA, Fan EH, Chapman DP, Freese EC, Trilk JL, Cureton KJ: Effects
of six weeks of quercetin supplementation on physical performance in
ROTC cadets. Mil Med 2010, 175:791–798.
159. Utter AC, Nieman DC, Kang J, Dumke CL, Quindry JC, McAnulty SR,
McAnulty LS: Quercetin does not affect rating of perceived exertion in
athletes during the Western States endurance run. Res Sports Med 2009,
160. Dumke CL, Nieman DC, Utter AC, Rigby MD, Quindry JC, Triplett NT,
McAnulty SR, McAnulty LS: Quercetin's effect on cycling efficiency and
substrate utilization. Appl Physiol Nutr Metab 2009, 34:993–1000.
161. Davis JM, Murphy EA, Carmichael MD, Davis B: Quercetin increases brain
and muscle mitochondrial biogenesis and exercise tolerance.
Am J Physiol Regul Integr Comp Physiol 2009, 296:R1071–1077.
162. Cureton KJ, Tomporowski PD, Singhal A, Pasley JD, Bigelman KA,
Lambourne K, Trilk JL, McCully KK, Arnaud MJ, Zhao Q: Dietary quercetin
supplementation is not ergogenic in untrained men. J Appl Physiol 2009,
163. Quindry JC, McAnulty SR, Hudson MB, Hosick P, Dumke C, McAnulty LS,
Henson D, Morrow JD, Nieman D: Oral quercetin supplementation and
blood oxidative capacity in response to ultramarathon competition. Int J
Sport Nutr Exerc Metab 2008, 18:601–616.
164. Henson D, Nieman D, Davis JM, Dumke C, Gross S, Murphy A, Carmichael
M, Jenkins DP, Quindry J, McAnulty S, et al: Post-160-km race illness
rates and decreases in granulocyte respiratory burst and salivary IgA
output are not countered by quercetin ingestion. Int J Sports Med 2008,
165. Nieman DC, Henson DA, Gross SJ, Jenkins DP, Davis JM, Murphy EA,
Carmichael MD, Dumke CL, Utter AC, McAnulty SR, et al: Quercetin reduces
illness but not immune perturbations after intensive exercise.
Med Sci Sports Exerc 2007, 39:1561–1569.
166. Nieman DC, Henson DA, Davis JM, Angela Murphy E, Jenkins DP, Gross SJ,
Carmichael MD, Quindry JC, Dumke CL, Utter AC, et al: Quercetin's
influence on exercise-induced changes in plasma cytokines and muscle
and leukocyte cytokine mRNA. J Appl Physiol 2007, 103:1728–1735.
167. Campbell B, Downing J, Kilpatrick M, La Bounty P, Elkins A, Williams S,
dos Santos MG: The effects of a commercially available energy drink
on resistance training and performance. Med Sci Sports Exerc 2010,
168. Forbes SC, Candow DG, Little JP, Magnus C, Chilibeck PD: Effect of Red Bull
energy drink on repeated Wingate cycle performance and bench-press
muscle endurance. Int J Sport Nutr Exerc Metab 2007, 17:433–444.
169. Hoffman JR, Kang J, Ratamess NA, Hoffman MW, Tranchina CP,
Faigenbaum AD: Examination of a pre-exercise, high energy supplement
on exercise performance. J Int Soc Sports Nutr 2009, 6:2.
170. Candow DG, Kleisinger AK, Grenier S, Dorsch KD: Effect of sugar-free Red
Bull energy drink on high-intensity run time-to-exhaustion in young
adults. J Strength Cond Res 2009, 23:1271–1275.
171. Cureton KJ, Warren GL, Millard-Stafford ML, Wingo JE, Trilk J, Buyckx M:
Caffeinated sports drink: ergogenic effects and possible mechanisms.
Int J Sport Nutr Exerc Metab 2007, 17:35–55.
172. Alford C, Cox H, Wescott R: The effects of red bull energy drink on human
performance and mood. Amino Acids 2001, 21:139–150.
173. Campbell B, Kilpatrick M, Wilborn C, La Bounty P, Parker B, Gomez B,
Elkins A, Williams S, Dos Santos JA: A commercially available energy drink
does not improve peak power on multiple 20-second Wingate tests.
J Int Soc Sports Nutr 2010, 7:P10.
174. Gonzalez AM, Walsh AL, Ratamess NA, Kang J, Hoffman JR: Effect of a
pre-workout energy supplement on acute multi-joint resistance exercise.
J Sports Sci Med 2011, 10:261–266.
175. Astorino TA, Matera AJ, Basinger J, Evans M, Schurman T, Marquez R:
Effects of red bull energy drink on repeated sprint performance in
women athletes. Amino Acids 2012, 42:1803–1808.
176. Haff GG, Koch AJ, Potteiger JA, Kuphal KE, Magee LM, Green SB, Jakicic JJ:
Carbohydrate supplementation attenuates muscle glycogen loss during
acute bouts of resistance exercise. Int J Sport Nutr Exerc Metab 2000,
177. Kulik JR, Touchberry CD, Kawamori N, Blumert PA, Crum AJ, Haff GG:
Supplemental carbohydrate ingestion does not improve performance of
high-intensity resistance exercise. J Strength Cond Res 2008, 22:1101–1107.
178. Lambert CP, Flynn MG, Boone JB Jr, Michaud TJ, Rodriguez-Zayas J:
Effects of carbohydrate feeding on multiple bout resistance exercised.
J Appl Sport Sci Res 1991, 5:192–197.
179. Walsh AL, Gonzalez AM, Ratamess NA, Kang J, Hoffman JR: Improved time
to exhaustion following ingestion of the energy drink Amino Impact.
J Int Soc Sports Nutr 2010, 7:14.
180. Currell K, Jeukendrup AE: Validity, reliability and sensitivity of measures of
sporting performance. Sports Med 2008, 38:297–316.
181. Laursen PB, Francis GT, Abbiss CR, Newton MJ, Nosaka K: Reliability of
time-to-exhaustion versus time-trial running tests in runners.
Med Sci Sports Exerc 2007, 39:1374–1379.
182. Scholey AB, Kennedy DO: Cognitive and physiological effects of an
"energy drink": an evaluation of the whole drink and of glucose, caffeine
and herbal flavouring fractions. Psychopharmacology (Berl) 2004, 176:320–330.
183. Smit HJ, Cotton JR, Hughes SC, Rogers PJ: Mood and cognitive
performance effects of "energy" drink constituents: caffeine, glucose and
carbonation. Nutr Neurosci 2004, 7:127–139.
184. Rao A, Hu H, Nobre AC: The effects of combined caffeine and glucose
drinks on attention in the human brain. Nutr Neurosci 2005, 8:141–153.
185. Howard MA, Marczinski CA: Acute effects of a glucose energy drink on
behavioral control. Exp Clin Psychopharmacol 2010, 18:553–561.
186. Pettitt RW, Niemeyer JD, Sexton PJ, Lipetzky A, Murray SR: Do the
non-caffeine ingredients of energy drinks affect metabolic responses to
heavy exercise? J Strength Cond Res 2012, [Epub ahead of print].
187. Bloomer RJ, Fisher-Wellman KH, Hammond KG, Schilling BK, Weber AA, Cole BJ:
Dietary supplement increases plasma norepinephrine, lipolysis, and
metabolic rate in resistance trained men. J Int Soc Sports Nutr 2009, 6:4.
188. Dulloo AG, Geissler CA, Horton T, Collins A, Miller DS: Normal caffeine
consumption: influence on thermogenesis and daily energy expenditure
in lean and postobese human volunteers. Am J Clin Nutr 1989, 49:44–50.
189. Jitomir J, Nassar E, Culbertson J, Moreillon J, Buford T, Hudson G, Cooke M,
Kreider R, Willoughby DS: The acute effects of the thermogenic
supplement Meltdown on energy expenditure, fat oxidation, and
hemodynamic responses in young, healthy males. J Int Soc Sports Nutr
190. Mendel RW, Hofheins JE: Metabolic responses to the acute ingestion of
two commercially available carbonated beverages: a pilot study. J Int Soc
Sports Nutr 2007, 4:7.
191. Rudelle S, Ferruzzi MG, Cristiani I, Moulin J, Mace K, Acheson KJ, Tappy L:
Effect of a thermogenic beverage on 24-hour energy metabolism in
humans. Obesity (Silver Spring) 2007, 15:349–355.
192. Taylor LW, Wilborn CD, Harvey T, Wismann J, Willoughby DS: Acute effects
of ingesting Java Fittrade mark energy extreme functional coffee on
resting energy expenditure and hemodynamic responses in male and
female coffee drinkers. J Int Soc Sports Nutr 2007, 4:10.
193. Wilborn C, Taylor L, Poole C, Bushey B, Williams L, Foster C, Campbell B:
Effects of ingesting a commercial thermogenic product on
hemodynamic function and energy expenditure at rest in males and
females. Appl Physiol Nutr Metab 2009, 34:1073–1078.
194. Roberts MD, Dalbo VJ, Hassell SE, Stout JR, Kerksick CM: Efficacy and safety
of a popular thermogenic drink after 28 days of ingestion.
J Int Soc Sports Nutr 2008, 5:19.
195. Dalbo VJ, Roberts MD, Stout JR, Kerksick CM: Acute effects of ingesting a
commercial thermogenic drink on changes in energy expenditure and
markers of lipolysis. J Int Soc Sports Nutr 2008, 5:6.
196. Dalbo VJ, Roberts MD, Stout JR, Kerksick CM: Effect of gender on the
metabolic impact of a commercially available thermogenic drink.
J Strength Cond Res 2010, 24:1633–1642.
197. Rashti SL, Ratamess NA, Kang J, Faigenbaum AD, Chilakos A, Hoffman JR:
Thermogenic effect of meltdown RTD energy drink in young healthy
women: a double blind, cross-over design study. Lipids Health Dis 2009,
198. Bloomer RJ, Canale RE, Blankenship MM, Hammond KG, Fisher-Wellman KH,
Schilling BK: Effect of the dietary supplement Meltdown on
catecholamine secretion, markers of lipolysis, and metabolic rate in men
and women: a randomized, placebo controlled, cross-over study.
Lipids Health Dis 2009, 8:32.
199. Stout J, Moon J, Tobkin S, Lockwood C, Smith A, Graef J, Kendall K, Beck T,
Cramer J: Pre-workout consumption of Celsius(R) enhances the benefits
of chronic exercise on body composition and cardiorespiratory fitness.
J Int Soc Sports Nutr 2008, 5:P8.
200. Higgins JP, Tuttle TD, Higgins CL: Energy beverages: content and safety.
Mayo Clin Proc 2010, 85:1033–1041.
201. Sepkowitz KA: Energy drinks and caffeine-related adverse effects.
JAMA 2012, :1–2 [Epub ahead of print].
202. Torpy JM, Livingston EH: Energy drinks. JAMA 2012, :1–1 [Epub ahead of
203. Howland JRDJ: Risks of energy drinks mixed with alcohol. JAMA 2012, :1–2
[Epub ahead of print].
204. Clauson KA, Shields KM, McQueen CE, Persad N: Safety issues associated
with commercially available energy drinks. J Am Pharm Assoc (2003) 2008,
48:e55–63. quiz e64-57.
205. Duchan E, Patel ND, Feucht C: Energy drinks: a review of use and safety
for athletes. Phys Sportsmed 2010, 38:171–179.
206. Lockwood CM, Moon JR, Smith AE, Tobkin SE, Kendall KL, Graef JL,
Cramer JT, Stout JR: Low-calorie energy drink improves physiological
response to exercise in previously sedentary men: a placebo-controlled
efficacy and safety study. J Strength Cond Res 2010, 24:2227–2238.
207. Pennington N, Johnson M, Delaney E, Blankenship MB: Energy drinks:
a new health hazard for adolescents. J Sch Nurs 2010, 26:352–359.
208. Weiss EP, Arif H, Villareal DT, Marzetti E, Holloszy JO: Endothelial function
after high-sugar-food ingestion improves with endurance exercise
performed on the previous day. Am J Clin Nutr 2008, 88:51–57.
209. Petit A, Levy F, Lejoyeux M, Reynaud M, Karila L: Energy drinks:
an unknown risk. Rev Prat 2012, 62:673–678.
210. Why isn't the amount of caffeine a product contains required of a food label?. http://www.fda.gov/AboutFDA/Transparency/Basics/uc...
211. Health Canada's proposed approach to managing caffeinated energy drinks. http:// www.hc-sc.gc.ca/fn-an/legislation/pol/energy-drink...
212. McCusker RR, Goldberger BA, Cone EJ: Caffeine content of specialty
coffees. J Anal Toxicol 2003, 27:520–522.
213. Jin KN, Chun EJ, Lee CH, Kim JA, Lee MS, Choi SI: Subclinical coronary
atherosclerosis in young adults: prevalence, characteristics, predictors
with coronary computed tomography angiography. Int J Cardiovasc
Imaging 2012, [Epub ahead of print].
214. Thiene G, Carturan E, Corrado D, Basso C: Prevention of sudden cardiac
death in the young and in athletes: dream or reality? Cardiovasc Pathol
215. Radojevic N, Bjelogrlic B, Aleksic V, Rancic N, Samardzic M, Petkovic S,
Savic S: Forensic aspects of water intoxication: four case reports and
review of relevant literature. Forensic Sci Int 2012, 220:1–5.
216. Holmgren P, Norden-Pettersson L, Ahlner J: Caffeine fatalities–four case
reports. Forensic Sci Int 2004, 139:71–73.
217. Kerrigan S, Lindsey T: Fatal caffeine overdose: two case reports.
Forensic Sci Int 2005, 153:67–69.
218. Rudolph T, Knudsen K: A case of fatal caffeine poisoning. Acta Anaesthesiol
Scand 2010, 54:521–523.
219. Nawrot P, Jordan S, Eastwood J, Rotstein J, Hugenholtz A, Feeley M:
Effects of caffeine on human health. Food Addit Contam 2003, 20:1–30.
220. Higdon JV, Frei B: Coffee and health: a review of recent human research.
Crit Rev Food Sci Nutr 2006, 46:101–123.
221. Usman A, Jawaid A: Hypertension in a young boy: an energy drink effect.
BMC Res Notes 2012, 5:591.
222. Worthley MI, Prabhu A, De Sciscio P, Schultz C, Sanders P, Willoughby SR:
Detrimental effects of energy drink consumption on platelet and
endothelial function. Am J Med 2010, 123:184–187.
223. Steinke L, Lanfear DE, Dhanapal V, Kalus JS: Effect of "energy drink"
consumption on hemodynamic and electrocardiographic parameters in
healthy young adults. Ann Pharmacother 2009, 43:596–602.
224. Adverse event reporting for dietary supplements: an inadequate safety valve. https://oig.hhs.gov/oei/reports/oei-01-00-00180.pd...